#Neuropharmacology #ClinicalPharmacology #CNSDrugs #DrugInteractions #Pharmacokinetics #Pharmacodynamics #Neuroscience To view or add a comment, sign in The liver plays a critical role in drug metabolism, transforming compounds into forms that can be utilised or eliminated
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Search terms included (prostate OR prostatic) AND (cancer OR carcinoma OR adenocarcinoma OR tumour OR tumour OR neoplasm) AND (metastatic OR metastasis OR lymph node or nodal) AND (metastasis directed therapy OR SABR OR ablation OR cryotherapy OR local therapy OR cytoreductive OR cytoreduction OR surgery OR prostatectomy OR radiation therapy OR radiotherapy OR external beam radiotherapy)
It is a synthetic 39-amino acid peptide that acts as an agonist at both the glucose-dependent insulinotropic polypeptide receptor (GIPR) and the glucagon-like peptide-1 receptor (GLP-1R), producing synergistic metabolic effects that exceed those of selective GLP-1 agonists in clinical trials
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Concentration formula Concentration (mg/mL) = Total peptide (mg) / Total water volume (mL) For a 10 mg vial: 10 mg / 2 mL = 5 mg/mL 10 mg / 3 mL = 3.33 mg/mL 10 mg / 4 mL = 2.5 mg/mL 10 mg / 5 mL = 2 mg/mL Dose volume formula Volume needed (mL) = Desired dose (mg) / Concentration (mg/mL) For 0.5 mg at 3.33 mg/mL: 0.5 / 3.33 = 0.15 mL Syringe units formula Units = Volume (mL) x 100 For 0.15 mL: 0.15 x 100 = 15 units Combined formula (all-in-one) Units = (Desired dose in mg / Concentration in mg/mL) x 100 This is the only formula you actually need
