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This review aims to synthesize the current state of knowledge from the specialized literature by providing an overview of ME/CFS case definition and diagnostic criteria, proposed etiologies, clinical manifestations, and the pathophysiological mechanisms underlying this heterogeneous condition, with particular emphasis on the interplay between the gut microbiome and ME/CFS

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[52] Healthcare providers should carefully weigh potential benefits against unknown risks when considering melatonin therapy in children and adolescents

To clarify the protective effects of Clostridium and its metabolites on -cells, researchers have conducted a series of targeted studies