Effects of retatrutide on body composition in people with type 2 diabetes: a substudy of a phase 2, double-blind, parallel-group, placebo-controlled, randomised trial
In 2023 a survey undertaken among 300 patients by Morgan Stanley revealed that the reduction in calorie intake per patient of between 20 and 30 percent could have 'long term implications for food-related businesses, particularly those selling unhealthier foods such as high-fat, sweet and salty products' (Economist)
The main risk during months 3 through 6 is complacency
Manufacturers must invest in early benchtop process development to model and optimize their continuous chromatography system, ensuring its right-sized to keep pace with intensified upstream operations
Phillips SA, van Santen HM, Hamilton JK, et al
Notably, researchers observed no similar reduction in hospitalizations unrelated to alcohol in T2D populations and smaller impacts on hospitalizations unrelated to alcohol in populations with obesity, suggesting the effect may be specific to alcohol-related outcomes, rather than confounding by underlying health status or general improvements in health
