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Keywords: vitamin B-12, folic acid, folate, holotranscobalamin, homocysteine, methylmalonic acid, pernicious anemia Statement of Significance : There is significant circumstantial evidence that excess folic acid consumption exacerbates vitamin B-12 insufficiency, but a biochemical/physiological mechanism has not yet been identified

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Conclusion Vitamin B12 injections can be a valuable tool for those with a deficiency or absorption issues, offering numerous health benefits, including increased energy, improved mood, and better metabolic function

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Gina Pastore, APRN-BC, MSN, ABAAHP, is a board-certified anti-aging specialist and founder of Vitality Aesthetic & Regenerative Medicine