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At the highest dose of 12 mg, participants lost an average of 24.2% of their body weight at 48 weeks

That does not mean GLP-1 medications are a problem

Consensus Recommendations on GLP-1 RA Use in the Management of Type 2 Diabetes Mellitus: South Asian Task Force

skin-specific effects were not highlighted as a primary safety signal, though injection site reactions were noted as expected with subcutaneous administration

That's a conversation to have before you enroll, not after

So I partnered with a team of researchers from Johns Hopkins Bloomberg School of Public Health to develop a set of principles for high-quality virtual weight loss carea benchmark against which we measured the 39 companies listed above