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An analysis of Irelands National Drug-Related Deaths Index from 2004 to 2013 revealed that more than two-thirds (31%~70%) of patients whose cause of death was epilepsy were alcohol dependent and had no ASMs in their bodies at the time of death (105)

Patients experiencing signs of allergic reactions should discontinue the medication and seek appropriate medical attention

Gastrointestinal side effects are the most commonly reported and include: Nausea (affecting 1040% of patients, depending on the specific GLP-1 agonist) Vomiting and diarrhoea (less common than nausea but can contribute to dehydration) Constipation (due to slowed gastric emptying) Abdominal discomfort or bloating These effects are typically most pronounced during treatment initiation and following dose increases

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semaglutide on HbA1c and weight in GLP-1 RA Nave patients with T2D