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The enzyme contains flavin adenine dinucleotide (FAD) as a prosthetic component, and as a result, normal enzyme activity is dependent on the dietary availability of riboflavin

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The mechanism is denaturationthermal energy breaks hydrogen bonds and disrupts disulfide bridges, causing the peptide to unfold from its active conformation into an inactive random coil

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5) Urine was collected after the 9 th dose of DMSA (or placebo) at the end of the 2 nd round in Phase 2