The choice always depends on the patient's metabolic status, diabetes, cardiovascular risk factors, baseline body mass index, and individual tolerance to therapy
the information below is extrapolated from authorised GLP-1 and GLP-1/GIP receptor agonists (such as semaglutide and tirzepatide) and should be interpreted accordingly
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Such speculation is therefore not a basis for clinical concern at this stage
Besides, geniposide suppressed A accumulation and alleviated cognitive dysfunction in APP/PS1 mice, attenuated A-induced reduction of LTP in acute hippocampal slices, and attenuated A-induced synaptic dysfunction in cultured hippocampal neurons (221, 222)
This is individual and requires experimentation guided by regular weigh-ins and ketone monitoring