Type 2 diabetes in adults: management (2015) [November 14]
Polycystic Ovary Syndrome (PCOS) - 5-10% of women 50% lower glutathione levels compared to women without PCOS 3-4x higher risk of preeclampsia 3x higher risk of gestational diabetes Critical concern: With 50% lower baseline glutathione, the "safe" dose is effectively cut in half IVF Conception - 2-5% of births (up to 6-8% in some countries) Women who conceive via IVF experience dramatic antioxidant depletion: 70% reduction in plasma antioxidant capacity 83% reduction in follicular fluid antioxidant capacity 50-100%+ increase in oxidative stress markers With over 5 million babies born via IVF globally, this represents a large high-risk population Gallbladder Dysfunction - 10% of pregnant women Up to 10% develop gallstones or biliary sludge Intrahepatic cholestasis: 0.4-10% of pregnancies CRITICAL: Fatal Outcomes Documented at Therapeutic Doses The first case of a pregnant woman with intrahepatic cholestasis who died from liver failure after taking THERAPEUTIC/NORMAL doses of acetaminophen was reported in 2022
In contrast, germline deletion of INHBA in mice is neonatally lethal, demonstrating the necessity of activin signaling during development 53
The platform also provides access to a registered dietitian for consultations, and the overall support level is high relative to its price point, with regular check-ins and nutritional guidance built into the program
Ther Adv Endocrinol Metab (2020) 11:133
Hydrogen itself has been reported to have anti-inflammatory effects in inflammatory diseases caused by various systemic inflammatory inducers 25 concanavalin A-induced hepatitis 10 , DSS-induced UC 9 , and LPS-induced sepsis 39
