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It has attracted scientific interest because of its possible protective and healing effects in preclinical models

When these enzymes are insufficient, vitamin B12 cannot be processed and absorbed normally

April 21, 2012

Noteworthy, our lab demonstrated that a clinically-used ROCK inhibitor, ripasudil, significantly enhanced hepatocyte engraftment and liver repopulation by blocking membrane attack complex (MAC) formation in vitro /vivo and thereby inhibiting KCs functions (Ma et al., 2023)

Fukada M, Watakabe I, YuasaKawada J, et al

Characterising this bidirectional relationship is an open research question, and the work is early-stage