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Energy transfer occurs when cAMP labeled with HTRF acceptor d2 (cAMP-d2) and the anti-cAMP antibody labeled with europium (Eu) as the energy donor (Anti-cAMP-Cryptate) are in proximity, resulting in the generation of fluorescence signal

Wide variation by country: The UK and Canada have the lowest drug shares (9% and 11%), while Japan and South Korea report the highest at about 20%

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