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Insulin sensitivity improvements manifest through multiple metabolic markers

Although the results are not directly comparable due to differences in study designs, what we know suggests retatrutide may be more effective

Frontiers in Endocrinology , 15 , Article 1431292

The resulting elimination half-life of approximately 6 days supports convenient once-weekly subcutaneous dosing

Serious events (like severe pancreatitis or major liver issues) have been rare and similar to placebo so far, but long-term safety is still being monitored in ongoing phase 3 programmes

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