Since ROS-dependent DNA damage is markedly increased in myeloid cells after Bcr-Abl transformation 18 , we hypothesize that blocking dTTP and dCTP supply might exacerbate replication stress and DNA damage in Bcr-Abl-transformed cells, thereby jeopardizing cell survival
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3 , control group: 3A and BPC 157 group: 3B )
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The New York Times, Sunday, December 16, 2001, Section 14NJ page 1 of the New York edition