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When you're conducting a study, you need to be absolutely certain that the compound you're working with at the end of the week is the same potent compound you started with

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The spray is imaged using high-speed photography or laser-sheet imaging, and the image is analyzed for: D max (the longest diameter of the spray cross-section), Dmin (the shortest diameter), and the ovality ratio (D max /D min ) a measure of how circular the spray is

In studies 3 and 4, a total dose of 2 mg was compared to placebo