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Combining them raises the risk of side effects without adding benefit
The structure of semaglutide consists of 31 amino acids with 94% homology to native human GLP-1
Thus, it doesnt seem likely that hypersensitivity to odors is the problem.[ref] Instead, much of the research points to hyper-reactivity to certain compounds, possibly due to altered detoxification pathways.[ref] Oxidative Stress in Multiple Chemical Sensitivity: Scientists have approached MCS from many angles, using genetic, metabolic, immunologic, etiologic, symptomatic, therapeutic, and epidemiologic tools
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One of the RCTs found significant mean improvements in Clinical Global Impressions-Improvement (CGI-I) score and cellular methylation capacity, but not in the Aberrant Behaviour Checklist (ABC), Social Responsiveness Scale (SRS) or GSH metabolism, with those who had the lowest methionine status at baseline (suggesting impaired methylation capacity) significantly more likely to respond to supplementation
