Transmission electron microscopy (TEM) results showed that NSBSO and NCBSO spontaneously assembled into spherical nanoparticles (NPs) after dissolving in phosphate buffered saline (PBS) solution with the concentration of 1 mM, with the average diameter of 48.26 6.17 nm and 41.27 6.62 nm, respectively (Fig
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Further analysis revealed adaptive metabolic reprogramming in a gene-dose-dependent manner, including downregulation of cholesterol biosynthesis (3-hydroxy-3-methylglutaryl-coenzyme A reductase, sterol-C5-desaturase, and 7-dehydrocholesterol reductase) and low-density lipoprotein receptor-mediated uptake pathways, coupled with enhanced cholesterol efflux (ATP-binding cassette subfamily G member 5/8)
Sonthalia, S., Jha, A
Different amounts of GSH were added to the solution, individually, to a final GSH concentration of 0, 1 and 10 mM
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