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Nitrous oxide misuse can cause vitamin B12 deficiency and absorption issues, which can lead to nerve damage, paralysis, chronic numbness, and loss of coordination

Cholinesterase inhibitors including Razadyne, Exelon and Aricept, disrupt the degradation of acetylcholine thus extending the half-life and availability of this neurotransmitter acting at central cholinergic muscarinic and nicotinic receptors [19-21]

Thus, DSIP helps to prevent excitotoxicity, which may underlie its neuroprotective action in cerebral ischemia[1]

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