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Wang C, Chen W, Jiang Y, Xiao X, Zou Q, Liang J, et al

Additionally, the high cost of these medications and potential issues with long-term adherence in real-world settings may impact the feasibility of indefinite treatment

Recommended Dosage: Take 2 capsules daily with a full glass of water, preferably with your morning meal for optimal absorption and sustained energy throughout the day

But the same 2025 review that catalogs those effects also underscores that only three human clinical trials have been published and that the compound remains investigational, with regulators having flagged it precisely because human safety and efficacy are not established

[109] However, some patients may experience sleep disturbances or vivid dreams with bedtime dosing, necessitating adjustment of administration timing

2000 Sep Nazzareno Ballatori, Suzanne M Krance, Sylvia Notenboom, Shujie Shi, Kim Tieu, Christine L Hammond