Taking two drugs from the same class could potentially increase the risk of side effects
Though results have not been published specifically in a Sjogrens disease cohort, it is likely that the robust effects on antibody and disease activity could be recapitulated in a Sjgrens disease population. However, even with so many new strategies under investigation, coupled with the excitement sparked by the rush of recent CAR T-cell trials, the idea that a potential cure is currently on the horizon remains premature, according to Isenberg
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interestingly, this disadvantage is cell lineagespecific because it does not affect, for instance, fibroblasts