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Research shows that NNMT inhibition promotes oxidative muscle fibers and preserves lean mass during weight loss

4 No additional precautions are needed

A classic example is curcumin, which has an oral bioavailability of less than 1% due to its low solubility in water, which makes it difficult to dissolve and absorb in the gastrointestinal tract, as well as its rapid chemical degradation at intestinal and hepatic pH [52]

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However, by altering the bodys metabolic rate and thermoregulation, some individuals might experience changes in their sweating patterns, though this is not a commonly reported effect

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