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BPC-157 may also help to reduce inflammation and may provide additional pain-reducing benefits based on inflammatory pain models: One murine study reported significant anti-inflammatory effects of BPC-157 on periodontal tissues in ligature-induced periodontitis [40]

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Several factors cause this: Lower stomach acid production [6] Less intrinsic factor [6] Interference from medications (especially proton pump inhibitors and metformin) [6] Atrophic gastritis affects 8-9% of adults over 65, which makes nutrient absorption even harder [7]

This review searched literature published between 2005 and 2021 using keywords cytokines, chemokines, protein targets, small molecular metabolites, and epigenetics, and summarizes recent advances in these novel targets