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Mdm2 Loss of Heterozygosity Cooperates with Mutant p53 in the Development of Acute Myeloid Leukemia

These hormones serve multiple functions in metabolic regulation

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MA significantly inhibited the polarization toward the M1 phenotype in microglia, indirectly fostering polarization toward the M2 phenotype, thus restoring the dynamic equilibrium of microglia

2.2 Dysregulation of neurotrophic support Brain-derived neurotrophic factor (BDNF) and its high-affinity receptor, tropomyosin receptor kinase B (TrkB), constitute a signaling axis fundamental to neuronal survival, differentiation, and synaptic plasticity within the central nervous system (Numakawa and Kajihara, 2025)

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