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Nucleic Acids 2 (2013)

27 However, when potential initiating events were investigated, the authors provided evidence that erastin inhibits system X c -, a Na + -independent cystine/glutamate antiporter responsible for cystine uptake into the cell, thereby promoting glutathione synthesis

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ROS have been documented to activate receptors of two main growth factors, EGF (epidermal growth factor) and PDGF (platelet-derived growth factor)

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