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While these medications are not primarily classified as hormonal therapies, their metabolic effects inevitably intersect with endocrine function, particularly in patients with obesity and insulin resistanceconditions known to disrupt multiple hormonal axes

Managing Stress Chronic stress can negatively impact both weight and blood pressure

4v) approach triggered by tumor-associated enzymes, where a peptide precursor undergoes specific cleavage and subsequent non-covalent co-assembly with ligand-conjugated peptides to form functional nano-PROTACs directly in diseased cells

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Olson MD, Junna MR