Many of these risks have been associated with cardiac remodeling due to damaged myocytes (heart muscle cells), and may impact surrounding tissues
The mechanisms underlying these potential synergistic effects remain under active investigation and may involve growth factor signaling, extracellular matrix synthesis, or anti-catabolic pathways in joint tissues
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According to NICE Technology Appraisal (TA875), Wegovy is recommended for adults with a BMI of at least 35 kg/m (or lower thresholds for certain ethnic groups) who have at least one weight-related comorbidity
Given the unmatched amount of information that can be obtained from a single scan, with increasingly faster and versatile protocols, CMR imaging will certainly add in the following years meaningful pieces to this complex puzzle
It acts as a filter for blue light to aid clear vision