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As a result, oxidative stress was reduced, while Natural Killer cells were twice as effective at fighting infections

39 KaciH.BodnrovS.Fliszr-NylE.LemliB.PelantovH.ValentovK.et al (2023)

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This particular co-activator mediates its function by binding to the NF-B target gene promoters in association with the RELA subunit of the NF-B family, thereby facilitating the transition between initiation and elongation

These data indicate that GSH depletion is directly responsible for the observed induction of NRF2 activity in Gclc L-KO mice