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1 OT2 OD026551
The GPX6 gene is located on chromosome 6p22.1 near the GPX5 gene and is composed of 5 exons that encode a 221 amino acid precursor protein
The resulting mitochondrial glutamate can exit the mitochondria into the cytosol, where this exported glutamate plays a role in the synthesis of important molecules, such as glutathione and non-essential amino acids (NEAAs)
Most of the patients decided for semaglutide for its weekly administration and higher efficacy in achieving weight loss compared to liraglutide [16]
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Furthermore, chondrocyte ferroptosis is a type of regulated cell death driven by the accumulation of lipid peroxides and disruption of redox homeostasis, which severely affects cartilage integrity (Yao et al., 2021)
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