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31 Predicting drug elimination based on half-life can go awry when very high doses of drugs are used, 32 as in the case of fluoxetine and the treatment of obsessive-compulsive disorder and when drugs are consumed in overdose

These agents modulate the SASP without killing the senescent cells

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Neuropeptides: metabolism to bioactive fragments and the pharmacology of their receptors

Zhang H, Yang K, Chen F, Liu Q, Ni J, Cao W, Hua Y, He F, Liu Z, Li L, Fan G

Glutathione and vitamin C are a logical supplement pairing based on their ability to work together to neutralize free radicals, combat oxidative stress and support a healthy inflammatory responselike "couple goals" for antioxidant supplementation