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Finally, GLP-1 has been demonstrated to increase cardiac output and heart rate

Mantle, D., & Hargreaves, I

The good news: clinical evidence shows no direct pharmacological interaction between GLP-1 agonists like semaglutide and oral contraceptives, intrauterine devices, or other hormonal methods

The brain pathways they affect appear to overlap with those driving addiction

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People with Type 2 diabetes prescribed semaglutide (Ozempic, Wegovy) had a significantly lower risk of an opioid OD than patients taking any of eight other diabetic medications, researchers found