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PMID: 19666465

One caution we repeat constantly in our practice: ramp up slowly and drink water, because when you increase fiber you also need enough fluids

Some users report needing more drinks to feel effects

Long-acting GLP-1R agonists do not reduce PPG to the same extent and do not exert the same effect on gastric motility after long-term use as short-acting agonists [9]

Fortunately, most can be avoided through careful preparation and consistent technique

Gut dysbiosis and reactive oxygen species (ROS)-induced oxidative stress contribute to the accumulation of -syn, which subsequently propagates to the brain via the vagus nerve, thereby establishing a gut-brain axis mechanism in disease progression (Soni et al., 2024)