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Metabolites from the PPP and an influx of amino acids following T cell activation provides the necessary building blocks for nucleic acid, protein, lipid, and carbohydrate anabolism ( The physiological metabolic shift that occurs following T cell activation and critical to productive HIV replication is partially driven by mTOR signaling

Anna Sandberg is an employee of Novo Nordisk A/S

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At the same time, circulating EGT levels were detected to be significantly lower in CD patients than in healthy individuals, which seems to make it a potential biomarker for CD (Lai et al., 2019)