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Safe Rates, GLP-1 Expectations, and Realistic Goals Wondering how much weight you can lose in a month

Yes, certain medications promote weight gain and can counteract GLP-1 effects, including antipsychotics (olanzapine, clozapine), mood stabilizers (valproate, lithium), some antidepressants (mirtazapine, paroxetine), corticosteroids, and diabetes medications like insulin or sulfonylureas

All treatments involve weekly or daily injections

Lifestyle modifications remain the cornerstone of safe weight management: Dietary interventions : A modest calorie deficit (typically 500600 kcal/day) achieved through balanced nutrition rather than restrictive dieting

Discomfort is minimal

Akiyama H, Tcheng M, Sharma P, Zhao R, Ostermann LB, Yazdani S, Moayed A, Szulc Z, Oleinik N, Mak PY, Ruvolo V, Carter BZ, Ogretmen B, Borthakur G, Schimmer, AD Andreeff M, and Ishizawa J