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Zhang Y, Okamura S, Kudo T, Masuo T, Mori M

There is a lack of long-term safety data in healthy adults

In light of the previous studies, anticoagulation with thrombin inhibitor dabigatran etexilate (DABI) reduces the early hepatotoxicity in AILI, but significantly exacerbates liver injury at 24 h after APAP administration due to the attenuated hepatocyte proliferation [64]

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Though the recommended doses are not expected to cause adverse effects for the infant, there are no human studies available to assess the risks

Then, the full-length genomic slcr-46.1 was fused with VENUS and expressed as a trans gene in wild-type worms under the slcr-46.1 promoter (Fig