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In our study, we did not utilize predictive sodium change equations like the Voets formula 22 , which is tailored for DDAVP clamping where urine osmolality is consistently fixed as in SIAD conditions

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While the movement symptoms of the lixisenatide group did not change compared to the start of the trial, the placebo group experienced worsening of their symptoms

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Conclusion If you have hypothyroidism and you are struggling to feel back to your normal self then it would be a good idea to evaluate your B12 levels and consider supplementation