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Patti ME, Goldfine AB
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The preclinical data supports a mechanism tied to somatotroph cell activation in the anterior pituitary
PEPerchini Scientific does not market this material for therapeutic, diagnostic, human or veterinary use and provides no dosing or administration guidance
Adverse Events Across Trials The safety pattern is consistent across the published trials: gastrointestinal events dominate, they are dose-related, mostly mild to moderate, concentrated during dose escalation, and partially mitigated by starting at 2 mg rather than 4 mg
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