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Divalent metal transporter 1 allows Fe 3 to enter the cytoplasm after conversion to Fe 2 by six transmembrane epithelial antigens of prostate 3 (STEAP3) inside the endosome

They also slow digestion, suppress appetite, and regulate blood sugar levels

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Maintaining adequate hydration is important, as dehydration from gastrointestinal symptoms can increase the risk of acute kidney injury

This targeted mechanism minimizes the risk of off-target effects and supports the compounds favorable safety profile

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