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The effects may also may vary by individual

Despite the clear role that a pro-oxidative shift in metabolism has in driving NSC proliferation/differentiation, it appears there is also a limit to how much ROS can be tolerated, as a number of studies have indicated that loss of superoxide dismutase (SOD) 1, 2, or 3 can bias NSC differentiation towards more astrocyte formation, decrease hippocampal neurogenesis, and impair cognitive function in irradiated mice (Rola et al., 2007

Savage, K

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