Zhang XY, Wang DG, Duan YH, Zheng XY, Lin Y, Liang SL (2020) Production of lycopene by metabolically engineered Pichia pastoris
However, it should be emphasized that use of caloric restriction to control for weight-dependent effects in DIO mouse studies may potentially introduce confounding effects on microbiome signatures due to significant compensatory changes in hunger sensation, feeding pattern, resting metabolic rate and gut morphology which may be disproportionately to that attained by appetite suppressants 80,81
However, extending the results of MC1R interaction with both - and -opioid systems raises the possibility that in dark-haired humans there is an endogenous pain inhibition system resulting from MC1R activation
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Additional information Edited by G Melino Supplementary Information accompanies this paper on Cell Death and Disease website Rights and permissions Cell Death and Disease is an open-access journal published by Nature Publishing Group
10.1021/acs.biochem.5c00012 85 NgS