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At the metabolic level, AOD 9604 promotes triglyceride hydrolysis while concurrently reducing lipogenic activity through modulation of enzymes such as acetyl-CoA carboxylase

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For cancer-specific cytotoxicity, superparamagnetic iron oxide NPs could specifically target the METC complexes, resulting in mitochondrial ROS production, which induced cancer cell death (He et al., 2016)

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