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In Vitro: Dihexa binds with high affinity to HGF and both dihexa and its parent compound Norleucine 1-AngIV induce c-Met phosphorylation in the presence of subthreshold concentrations of HGF and augment HGF-dependent cell scattering. Further, dihexa and Nle1-AngIV induce hippocampal spinogenesis and synaptogenesis similar to HGF itself. Dihexa effectively inhibits HGF dimerization at 1 M. While dihexa at 1 nM and 10 pM alone does not activate c-Met, it markedly augments the capacity of HGF at 1.25 and 2.5 ng/mL to activate c-Met

Nature 410 , 701705 (2001)

Rather than mimicking gut hormones, Contrave works directly in the brain

The potential of ethylene oxide to cause teratogenic or adverse reproductive effects has been examined in 4 animal species (mouse, rat, rabbit, and monkey) by 2 routes of administration

Long-Term Foes: Sun Abuse and Tattoo Colors Excessive sun exposure can lead to more detrimental effects on your tattoos over time

Complete peptide list catalogs available compounds with brief descriptions of each