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Yes, glutathione works more effectively when combined with nutrients like vitamin C, selenium, and N acetyl cysteine

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FEBS Lett 382:213217 Dixon DP, Hawkins T, Hussey PJ, Edwards R (2009) Enzyme activities and subcellular localization of members of the Arabidopsis glutathione transferase superfamily

Antioxidant support is not an overnight fix

Here's a comparison of their key differences: How NAD+ Helps with Addiction Recovery NAD+ IV therapy has shown promise in supporting individuals recovering from addiction