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Retrieved from Fory, A., et al
Glutathione S transferase (GST) is the main intracellular antioxidant synthetized by Glutamate-Cysteine ligase and glutathione synthase, as demonstrated by Chen et al., 2007 in a study including with Gclc Knockout mice, which developed steatosis in very early ages [65]
Our findings showed that liver-specific Gclc deletion results in increased Nrf2 activity, impaired expression of lipogenic enzymes, and decreased circulating triglycerides
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Thats why we only work with state-regulated compounding pharmacies that adhere to strict regulatory standards