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In the early stage of MASLD, autophagy inhibits apoptosis (87), while in the late stage, autophagy is pro-apoptotic, which also indicates that autophagy is involved in the whole stage of MASLD development (87)
The subsequent increase in metabolic rate leads to a reduction in white adipose tissue and has been shown to produce significant weight loss in preclinical studies without affecting appetite
Further analysis revealed links between changes to sense of taste and appetite and satiety
Inhibition of SGLT2 leads to the decrease in blood glucose due to the increase in renal glucose excretion
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