Furthermore it was illustrated that multiple lysosomotropic compounds can redistribute the mannose 6-phosphate receptor from the trans-Golgi network to endosomes and concomitantly increase the secretion of lysosomal enzymes, resulting in a decline of intracellular lysosomal enzyme levels [36], which could further exacerbate the lysosomal dysfunction
That combination is why clinicians and patients started asking about this class
Kahne T, Lendeckel U, Wrenger S, Neubert K, Ansorge S, Reinhold D
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Do not attempt to salvage or filter the solution reconstitute a fresh vial using aseptic technique
