"It's prescribed by the doctor, the person takes their medicine, they lose weight, but then life happens," Cook said
Many patients remain on tirzepatide at a stable dose to prevent weight regain, as appetite and metabolic drive typically rebound after medication discontinuation
And the people who struggle
"Approving the oral formulation of Wegovy [semaglutide] reaffirms the establishments commitment to promoting the pharmaceutical ecosystem and reinforcing a proactive approach to addressing obesity and overweight challenges, said Dr Fatima Al Kaabi, director general of the Emirates Drug Establishment
, GLP-1 RA : ()
GLP-1 receptor agonists (semaglutide, liraglutide) are broken down by enzymes throughout the body rather than through liver metabolism Clinical evidence shows these medications may reduce liver fat content and improve liver enzyme levels through weight loss and improved insulin sensitivity Gallbladder disorders including gallstones and cholecystitis occur more frequently during treatment, particularly with rapid weight loss Patients with severe hepatic impairment (Child-Pugh class C) require specialist hepatology input before initiating treatment Baseline liver function tests should be considered before starting treatment, particularly in patients with risk factors for liver disease Immediate medical attention is required for jaundice, severe abdominal pain, fever with abdominal pain, or unexplained bruising during treatment Table of Contents Understanding Weight Loss Injections and Liver Health How GLP-1 Receptor Agonists Affect the Liver Potential Liver-Related Side Effects and Risks Who Should Avoid Weight Loss Injections Due to Liver Concerns Monitoring Liver Function During Treatment When to Seek Medical Advice About Liver Health Frequently Asked Questions Understanding Weight Loss Injections and Liver Health Weight loss injections, particularly GLP-1 receptor agonists such as semaglutide (Wegovy, Ozempic) and liraglutide (Saxenda), have become increasingly popular for managing obesity and type 2 diabetes in the UK
