At standard doses used for diabetes (Rybelsus 14mg or Ozempic 1mg), both forms lead to modest weight loss typically around 6-12 pounds over six months
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References: Adamou A, Barkas F, Milionis H, Ntaios G
As reviewed, there is good evidence of renoprotection across many of the GLP1RA trials (Table 3) and SGLT2i trials (Table 1), including recent evidence on the use of canagliflozin in the CREDENCE trial focused on patients with T2DM and diabetic nephropathy, and of dulaglutide in the AWARD7 trial
You might think you will lose your appetite completely and lose weight very fast, leading to side effects or drastic changes to your appearance