Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled trials
When to Speak to Your Doctor About Your Progress Contact your doctor if you experience persistent gastrointestinal symptoms, signs of pancreatitis or dehydration, gallbladder symptoms, hypoglycaemia, or unexplained palpitations
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Pacing your dose escalation according to tolerancesometimes staying at one level for an extra weekallows your system to adjust without derailing treatment
Note: BALANCE itself costs Medicare $16.7 billion per year at steady state (not a saving)
Adjust protocols accordingly
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