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Discussion at the American Heart Association session underscored the stakes of such decisions, as it was noted that an estimated 6.6 million American adults meet the inclusion criteria for the SELECT trial

[2] Liu X, Zhang Y, Zheng SY, et al

Retatrutide treatment produces favorable shifts in lipid metabolism

Regarding lack of access to the Bridge Program, we want to clarify the following: Under federal law, Medicare Part D plans cannot cover medications prescribed for weight loss Medications that are FDA-approved for both weight loss and other indications may only be covered by Part D plans for non-weight loss indications. This Bridge Program is a trial of a way to address the particular problem of Part D restrictions on weight-loss prescriptions

However, it is unclear how tirzepatide increases potency and what role GIP receptor agonism plays [80]