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GLP-1 receptor agonists also enhance serotonin receptor activity in specific brain regions

GLP-1 drug claims rose from 6.9% of employer plans in 2023 to 10.5% in 2025, according to Blue Cross Blue Shield data

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15 Alcohol can also worsen the nausea some people experience on Wegovy, particularly during dose escalation

The SURMOUNT trials showed average weight loss of up to 22 percent of body weight at the highest dose, making it the most effective GLP-1 class medication currently available