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Patients with Cushing syndrome can develop tolerance to and dependence on excessive endogenous cortisol, and hence, suffer from glucocorticoid withdrawal syndrome postoperatively.76 After resection, glucocorticoid taper is indicated until the HPAA recovers

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Increased intestinal permeability is facilitated by a high-fat diet (HFD) 22 , and may allow for bacterial translocation from the gut to adipose tissue 23

doi: 10.1016/s0006-2952(98)00227-5